Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide

Peptidoglycan-derived muramyl dipeptide (MDP) activates innate immunity via the host sensor NOD2. Although MDP is N-acetylated in most bacteria, mycobacteria and related Actinomycetes convert their MDP to an N-glycolylated form through the action of N-acetyl muramic acid hydroxylase (NamH). We used...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Coulombe, François, Divangahi, Maziar, Veyrier, Frédéric, de Léséleuc, Louis, Gleason, James L., Yang, Yibin, Kelliher, Michelle A., Pandey, Amit K., Sassetti, Christopher M., Reed, Michael B., Behr, Marcel A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722178/
https://ncbi.nlm.nih.gov/pubmed/19581406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081779
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars