Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae

The innate immune system recognizes microbial pathogens via pattern recognition receptors. One such receptor, NOD2, via recognition of muramyl dipeptide (MDP), triggers a distinct network of innate immune responses, including the production of interleukin-32 (IL-32), which leads to the differentiati...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Schenk, Mirjam, Mahapatra, Sebabrata, Le, Phuonganh, Kim, Hee Jin, Choi, Aaron W., Brennan, Patrick J., Belisle, John T., Modlin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995902/
https://ncbi.nlm.nih.gov/pubmed/27297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00334-16
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