Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae

The innate immune system recognizes microbial pathogens via pattern recognition receptors. One such receptor, NOD2, via recognition of muramyl dipeptide (MDP), triggers a distinct network of innate immune responses, including the production of interleukin-32 (IL-32), which leads to the differentiati...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Schenk, Mirjam, Mahapatra, Sebabrata, Le, Phuonganh, Kim, Hee Jin, Choi, Aaron W., Brennan, Patrick J., Belisle, John T., Modlin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995902/
https://ncbi.nlm.nih.gov/pubmed/27297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00334-16
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