Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae

The innate immune system recognizes microbial pathogens via pattern recognition receptors. One such receptor, NOD2, via recognition of muramyl dipeptide (MDP), triggers a distinct network of innate immune responses, including the production of interleukin-32 (IL-32), which leads to the differentiati...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Schenk, Mirjam, Mahapatra, Sebabrata, Le, Phuonganh, Kim, Hee Jin, Choi, Aaron W., Brennan, Patrick J., Belisle, John T., Modlin, Robert L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995902/
https://ncbi.nlm.nih.gov/pubmed/27297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00334-16
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