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Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide
Peptidoglycan-derived muramyl dipeptide (MDP) activates innate immunity via the host sensor NOD2. Although MDP is N-acetylated in most bacteria, mycobacteria and related Actinomycetes convert their MDP to an N-glycolylated form through the action of N-acetyl muramic acid hydroxylase (NamH). We used...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722178/ https://ncbi.nlm.nih.gov/pubmed/19581406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081779 |
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