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NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis

While the recognition of microbial infection often occurs at the cell surface via Toll-like receptors, the cytosol of the cell is also under surveillance for microbial products that breach the cell membrane. An important outcome of cytosolic recognition is the induction of IFNα and IFNβ, which are c...

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Detalhes bibliográficos
Main Authors: Pandey, Amit K., Yang, Yibin, Jiang, Zhaozhao, Fortune, Sarah M., Coulombe, Francois, Behr, Marcel A., Fitzgerald, Katherine A., Sassetti, Christopher M., Kelliher, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698121/
https://ncbi.nlm.nih.gov/pubmed/19578435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000500
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