XIAP mediates NOD signaling via interaction with RIP2

NOD1 and NOD2 are members of the NOD-like receptor (NLR) protein family that are involved in sensing the presence of pathogens and are a component of the innate immune system. Upon activation by specific bacterial peptides derived from peptidoglycans, NODs interact via a CARD-CARD interaction with t...

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Autors principals: Krieg, Andreas, Correa, Ricardo G., Garrison, Jason B., Le Negrate, Gaëlle, Welsh, Kate, Huang, Ziwei, Knoefel, Wolfram T., Reed, John C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732880/
https://ncbi.nlm.nih.gov/pubmed/19667203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907131106
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