ARTS and Siah Collaborate in a Pathway for XIAP Degradation

ARTS (Apoptosis-Related protein in the TGF-β Signaling pathway) is a mitochondrial protein that binds XIAP (X-linked Inhibitor of Apoptosis Protein) upon entering the cytosol, thus promoting cell death. Expression of ARTS is lost in some malignancies. Here we show that ARTS binds to XIAP at BIR1, a...

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Detalhes bibliográficos
Main Authors: Garrison, Jason B., Correa, Ricardo G., Gerlic, Motti, Yip, Kenneth W., Krieg, Andreas, Tamble, Craig M., Shi, Ranxin, Welsh, Kate, Duggineni, Srinivas, Huang, Ziwei, Ren, Keqin, Du, Chunying, Reed, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017644/
https://ncbi.nlm.nih.gov/pubmed/21185211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.002
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