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TWO MODES OF DEGRADATION OF THE TRAMTRACK TRANSCRIPTION FACTORS BY SIAH HOMOLOGUES

The Siah proteins, mammalian homologues of the Drosophila Sina protein, function as E3 ubiquitin ligase enzymes to target a wide range of cellular proteins for degradation. We report here a novel Drosophila protein that is homologous to Sina, named Sina-Homologue (SinaH). We show that it can direct...

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Bibliographic Details
Main Authors: Cooper, Sarah E., Murawsky, Christopher M., Lowe, Nicholas, Travers, Andrew A.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655653/
https://ncbi.nlm.nih.gov/pubmed/17962185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707765200
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