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ARTS and Siah Collaborate in a Pathway for XIAP Degradation

ARTS (Apoptosis-Related protein in the TGF-β Signaling pathway) is a mitochondrial protein that binds XIAP (X-linked Inhibitor of Apoptosis Protein) upon entering the cytosol, thus promoting cell death. Expression of ARTS is lost in some malignancies. Here we show that ARTS binds to XIAP at BIR1, a...

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Bibliografiske detaljer
Main Authors: Garrison, Jason B., Correa, Ricardo G., Gerlic, Motti, Yip, Kenneth W., Krieg, Andreas, Tamble, Craig M., Shi, Ranxin, Welsh, Kate, Duggineni, Srinivas, Huang, Ziwei, Ren, Keqin, Du, Chunying, Reed, John C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017644/
https://ncbi.nlm.nih.gov/pubmed/21185211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.002
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