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ARTS and Siah Collaborate in a Pathway for XIAP Degradation
ARTS (Apoptosis-Related protein in the TGF-β Signaling pathway) is a mitochondrial protein that binds XIAP (X-linked Inhibitor of Apoptosis Protein) upon entering the cytosol, thus promoting cell death. Expression of ARTS is lost in some malignancies. Here we show that ARTS binds to XIAP at BIR1, a...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017644/ https://ncbi.nlm.nih.gov/pubmed/21185211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.002 |
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