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The Molecular Recognition of Muramyl Dipeptide Occurs in the Leucine-rich Repeat Domain of Nod2

Genetic mutations in the innate immune receptor nucleotide-binding oligomerization domain-containing 2 (Nod2) have demonstrated increased susceptibility to Crohn’s disease, an inflammatory bowel disease which is hypothesized to be accompanied by changes in the gut microbiota. Nod2 responds to the pr...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Lauro, Mackenzie L., D’Ambrosio, Elizabeth A., Bahnson, Brian J., Grimes, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820023/
https://ncbi.nlm.nih.gov/pubmed/27748583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00154
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