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Designed leucine‐rich repeat proteins bind two muramyl dipeptide ligands
Designed protein receptors hold diagnostic and therapeutic promise. We now report the design of five consensus leucine‐rich repeat proteins (CLRR4–8) based on the LRR domain of nucleotide‐binding oligomerization domain (NOD)‐like receptors involved in the innate immune system. The CLRRs bind muramyl...
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| Publicat a: | Protein Sci |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Inc.
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7980508/ https://ncbi.nlm.nih.gov/pubmed/33512005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4031 |
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