Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

Growing evidence suggests water-soluble, non-fibrillar forms of amyloid-β protein (Aβ) have important roles in Alzheimer’s disease with toxicities mimicked by synthetic Aβ(1–42). However, no defined toxic structures acting via specific receptors have been identified and roles of proposed receptors,...

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Главные авторы: Nicoll, Andrew J., Panico, Silvia, Freir, Darragh B., Wright, Daniel, Terry, Cassandra, Risse, Emmanuel, Herron, Caroline E., O’Malley, Tiernan, Wadsworth, Jonathan D. F., Farrow, Mark A., Walsh, Dominic M., Saibil, Helen R., Collinge, John
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908552/
https://ncbi.nlm.nih.gov/pubmed/24022506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3416
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