Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

Growing evidence suggests water-soluble, non-fibrillar forms of amyloid-β protein (Aβ) have important roles in Alzheimer’s disease with toxicities mimicked by synthetic Aβ(1–42). However, no defined toxic structures acting via specific receptors have been identified and roles of proposed receptors,...

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Hlavní autoři: Nicoll, Andrew J., Panico, Silvia, Freir, Darragh B., Wright, Daniel, Terry, Cassandra, Risse, Emmanuel, Herron, Caroline E., O’Malley, Tiernan, Wadsworth, Jonathan D. F., Farrow, Mark A., Walsh, Dominic M., Saibil, Helen R., Collinge, John
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908552/
https://ncbi.nlm.nih.gov/pubmed/24022506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3416
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