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Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines
ETS transcription factors mediate a wide array of cellular functions and are attractive targets for pharmacological control of gene regulation. We report the inhibition of the ETS-family member PU.1 with a panel of novel heterocyclic diamidines. These diamidines are derivatives of furamidine (DB75)...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902942/ https://ncbi.nlm.nih.gov/pubmed/24157839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt955 |
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