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Single-molecule tracking of the transcription cycle by sub-second RNA detection
Transcription is an inherently stochastic, noisy, and multi-step process, in which fluctuations at every step can cause variations in RNA synthesis, and affect physiology and differentiation decisions in otherwise identical cells. However, it has been an experimental challenge to directly link the s...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901038/ https://ncbi.nlm.nih.gov/pubmed/24473079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01775 |
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