Transcription initiation by human RNA polymerase II visualized at single-molecule resolution

Forty years of classical biochemical analysis have identified the molecular players involved in initiation of transcription by eukaryotic RNA polymerase II (Pol II) and largely assigned their functions. However, a dynamic picture of Pol II transcription initiation and an understanding of the mechani...

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Bibliographic Details
Main Authors: Revyakin, Andrey, Zhang, Zhengjian, Coleman, Robert A., Li, Yan, Inouye, Carla, Lucas, Julian K., Park, Sang-Ryul, Chu, Steven, Tjian, Robert
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418587/
https://ncbi.nlm.nih.gov/pubmed/22810624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.194936.112
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