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Single-molecule tracking of the transcription cycle by sub-second RNA detection

Transcription is an inherently stochastic, noisy, and multi-step process, in which fluctuations at every step can cause variations in RNA synthesis, and affect physiology and differentiation decisions in otherwise identical cells. However, it has been an experimental challenge to directly link the s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhang, Zhengjian, Revyakin, Andrey, Grimm, Jonathan B, Lavis, Luke D, Tjian, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901038/
https://ncbi.nlm.nih.gov/pubmed/24473079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01775
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