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Single-molecule tracking of the transcription cycle by sub-second RNA detection

Transcription is an inherently stochastic, noisy, and multi-step process, in which fluctuations at every step can cause variations in RNA synthesis, and affect physiology and differentiation decisions in otherwise identical cells. However, it has been an experimental challenge to directly link the s...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Zhengjian, Revyakin, Andrey, Grimm, Jonathan B, Lavis, Luke D, Tjian, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901038/
https://ncbi.nlm.nih.gov/pubmed/24473079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01775
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