Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis

Transcription of protein-encoding genes in eukaryotic cells requires the coordinated action of multiple general transcription factors (GTFs) and RNA polymerase II (Pol II). A “step-wise” preinitiation complex (PIC) assembly model has been suggested based on conventional ensemble biochemical measurem...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Zhang, Zhengjian, English, Brian P., Grimm, Jonathan B., Kazane, Stephanie A., Hu, Wenxin, Tsai, Albert, Inouye, Carla, You, Changjiang, Piehler, Jacob, Schultz, Peter G., Lavis, Luke D., Revyakin, Andrey, Tjian, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066616/
https://ncbi.nlm.nih.gov/pubmed/27798851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.285395.116
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