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Single-molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
Enhancer-binding pluripotency regulators (Sox2 and Oct4) play a seminal role in embryonic stem (ES) cell specific gene regulation. Here, we combine in vivo and in vitro single-molecule imaging, transcription factor (TF) mutagenesis and ChIP-exo mapping to determine how TFs dynamically search for and...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040518/ https://ncbi.nlm.nih.gov/pubmed/24630727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.062 |
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