Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...

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Sparad:
Bibliografiska uppgifter
I publikationen:Genes Dev
Huvudupphovsmän: Eychenne, Thomas, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Boschiero, Claire, Peixeiro, Nuno, Cornu, David, Redeker, Virginie, Kuras, Laurent, Nicolas, Pierre, Werner, Michel, Soutourina, Julie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066617/
https://ncbi.nlm.nih.gov/pubmed/27688401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.285775.116
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