Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Eychenne, Thomas, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Boschiero, Claire, Peixeiro, Nuno, Cornu, David, Redeker, Virginie, Kuras, Laurent, Nicolas, Pierre, Werner, Michel, Soutourina, Julie
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066617/
https://ncbi.nlm.nih.gov/pubmed/27688401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.285775.116
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