Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...

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Vydáno v:Genes Dev
Hlavní autoři: Eychenne, Thomas, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Boschiero, Claire, Peixeiro, Nuno, Cornu, David, Redeker, Virginie, Kuras, Laurent, Nicolas, Pierre, Werner, Michel, Soutourina, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066617/
https://ncbi.nlm.nih.gov/pubmed/27688401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.285775.116
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