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Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Eychenne, Thomas, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Boschiero, Claire, Peixeiro, Nuno, Cornu, David, Redeker, Virginie, Kuras, Laurent, Nicolas, Pierre, Werner, Michel, Soutourina, Julie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066617/
https://ncbi.nlm.nih.gov/pubmed/27688401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.285775.116
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