Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo

Mediator is a large multiprotein complex conserved in all eukaryotes, which has a crucial coregulator function in transcription by RNA polymerase II (Pol II). However, the molecular mechanisms of its action in vivo remain to be understood. Med17 is an essential and central component of the Mediator...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Eyboulet, Fanny, Wydau-Dematteis, Sandra, Eychenne, Thomas, Alibert, Olivier, Neil, Helen, Boschiero, Claire, Nevers, Marie-Claire, Volland, Hervé, Cornu, David, Redeker, Virginie, Werner, Michel, Soutourina, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627066/
https://ncbi.nlm.nih.gov/pubmed/26240385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv782
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