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eIF2α interactions with mRNA control accurate start codon selection by the translation preinitiation complex
In translation initiation, AUG recognition triggers rearrangement of the 48S preinitiation complex (PIC) from an open conformation to a closed state with more tightly-bound Met-tRNA(i). Cryo-EM structures have revealed interactions unique to the closed complex between arginines R55/R57 of eIF2α with...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544238/ https://ncbi.nlm.nih.gov/pubmed/32955564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa761 |
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