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Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity

Transcription by RNA polymerase II (Pol II) is a complex process that requires general transcription factors and Pol II to assemble on DNA into preinitiation complexes that can begin RNA synthesis upon binding of NTPs (nucleoside triphosphate). The pathways by which preinitiation complexes form, and...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Horn, Abigail E., Kugel, Jennifer F., Goodrich, James A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009721/
https://ncbi.nlm.nih.gov/pubmed/27112574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw321
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