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Formation and Fate of a Complete 31-Protein RNA Polymerase II Transcription Preinitiation Complex

Whereas individual RNA polymerase II (pol II)-general transcription factor (GTF) complexes are unstable, an assembly of pol II with six GTFs and promoter DNA could be isolated in abundant homogeneous form. The resulting complete pol II transcription preinitiation complex (PIC) contained equimolar am...

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Autors principals: Murakami, Kenji, Calero, Guillermo, Brown, Christopher R., Liu, Xin, Davis, Ralph E., Boeger, Hinrich, Kornberg, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585067/
https://ncbi.nlm.nih.gov/pubmed/23303183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433623
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