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Requirements for RNA polymerase II preinitiation complex formation in vivo

Transcription by RNA polymerase II requires assembly of a preinitiation complex (PIC) composed of general transcription factors (GTFs) bound at the promoter. In vitro, some GTFs are essential for transcription, whereas others are not required under certain conditions. PICs are stable in the absence...

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Pubblicato in:eLife
Autori principali: Petrenko, Natalia, Jin, Yi, Dong, Liguo, Wong, Koon Ho, Struhl, Kevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366898/
https://ncbi.nlm.nih.gov/pubmed/30681409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43654
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