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Requirements for RNA polymerase II preinitiation complex formation in vivo

Transcription by RNA polymerase II requires assembly of a preinitiation complex (PIC) composed of general transcription factors (GTFs) bound at the promoter. In vitro, some GTFs are essential for transcription, whereas others are not required under certain conditions. PICs are stable in the absence...

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Publicado en:eLife
Autores principales: Petrenko, Natalia, Jin, Yi, Dong, Liguo, Wong, Koon Ho, Struhl, Kevin
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366898/
https://ncbi.nlm.nih.gov/pubmed/30681409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43654
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