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Requirements for RNA polymerase II preinitiation complex formation in vivo

Transcription by RNA polymerase II requires assembly of a preinitiation complex (PIC) composed of general transcription factors (GTFs) bound at the promoter. In vitro, some GTFs are essential for transcription, whereas others are not required under certain conditions. PICs are stable in the absence...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Petrenko, Natalia, Jin, Yi, Dong, Liguo, Wong, Koon Ho, Struhl, Kevin
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366898/
https://ncbi.nlm.nih.gov/pubmed/30681409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43654
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