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Requirements for RNA polymerase II preinitiation complex formation in vivo

Transcription by RNA polymerase II requires assembly of a preinitiation complex (PIC) composed of general transcription factors (GTFs) bound at the promoter. In vitro, some GTFs are essential for transcription, whereas others are not required under certain conditions. PICs are stable in the absence...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Petrenko, Natalia, Jin, Yi, Dong, Liguo, Wong, Koon Ho, Struhl, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366898/
https://ncbi.nlm.nih.gov/pubmed/30681409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43654
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