Yeast NC2 Associates with the RNA Polymerase II Preinitiation Complex and Selectively Affects Transcription In Vivo

NC2 (Dr1-Drap1 or Bur6-Ydr1) has been characterized in vitro as a general negative regulator of RNA polymerase II (Pol II) transcription that interacts with TATA-binding protein (TBP) and inhibits its function. Here, we show that NC2 associates with promoters in vivo in a manner that correlates with...

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Detalhes bibliográficos
Main Authors: Geisberg, Joseph V., Holstege, Frank C., Young, Richard A., Struhl, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86904/
https://ncbi.nlm.nih.gov/pubmed/11283253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2736-2742.2001
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