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The roles of TAF1 in neuroscience and beyond

The transcriptional machinery is essential for gene expression and regulation; dysregulation of transcription can result in a range of pathologies, including neurodegeneration, cancer, developmental disorders and cardiovascular disease. A key component of RNA polymerase II-mediated transcription is...

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Principais autores: Elisa M. Crombie, Karen Cleverley, H. T. Marc Timmers, Elizabeth M. C. Fisher
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2024-09-01
coleção:Royal Society Open Science
Assuntos:
TATA box binding-protein (TBP)-associated factor 1
TAF1
X-linked dystonia–parkinsonism
X-linked intellectual disability
TFIID
RNA polymerase II
Acesso em linha:https://royalsocietypublishing.org/doi/10.1098/rsos.240790
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