Yeast NC2 Associates with the RNA Polymerase II Preinitiation Complex and Selectively Affects Transcription In Vivo

NC2 (Dr1-Drap1 or Bur6-Ydr1) has been characterized in vitro as a general negative regulator of RNA polymerase II (Pol II) transcription that interacts with TATA-binding protein (TBP) and inhibits its function. Here, we show that NC2 associates with promoters in vivo in a manner that correlates with...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Geisberg, Joseph V., Holstege, Frank C., Young, Richard A., Struhl, Kevin
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 2001
נושאים:	Transcriptional Regulation
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.8.2736-2742.2001
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