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Requirements for RNA polymerase II preinitiation complex formation in vivo

Transcription by RNA polymerase II requires assembly of a preinitiation complex (PIC) composed of general transcription factors (GTFs) bound at the promoter. In vitro, some GTFs are essential for transcription, whereas others are not required under certain conditions. PICs are stable in the absence...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Petrenko, Natalia, Jin, Yi, Dong, Liguo, Wong, Koon Ho, Struhl, Kevin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366898/
https://ncbi.nlm.nih.gov/pubmed/30681409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43654
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