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Polycomb Repressive Complex 1 (PRC1) Disassembles RNA Polymerase II Preinitiation Complexes

Despite the important role of Polycomb in genome-wide silencing, little is known of the specific biochemical mechanism by which it inactivates transcription. Here we address how recombinant Polycomb repressive complex 1 (PRC1) inhibits activated RNA polymerase II preinitiation complex (PIC) assembly...

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Detalles Bibliográficos
Main Authors: Lehmann, Lynn, Ferrari, Roberto, Vashisht, Ajay A., Wohlschlegel, James A., Kurdistani, Siavash K., Carey, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476247/
https://ncbi.nlm.nih.gov/pubmed/22910904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397430
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