Mediator and SAGA Have Distinct Roles in Pol II Preinitiation Complex Assembly and Function

A key feature of RNA polymerase II preinitiation complexes (PICs) is their ability to coordinate transcription initiation with chromatin modification and remodeling. To understand how this coordination is achieved, we employed extensive proteomic and mechanistic analyses to study the composition and...

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Detalhes bibliográficos
Main Authors: Chen, Xiao-Fen, Lehmann, Lynn, Lin, Justin J., Vashisht, Ajay, Schmidt, Ryan, Ferrari, Roberto, Huang, Chengyang, McKee, Robin, Mosley, Amber, Plath, Kathrin, Kurdistani, Siavash K., Wohlschlegel, James, Carey, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513640/
https://ncbi.nlm.nih.gov/pubmed/23177621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.019
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