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Structural basis of preinitiation complex assembly on human pol II promoters.
Transcription initiation requires the assembly of a preinitiation complex (PIC), which is nucleated through binding of the TATA-box binding protein (TBP) to the promoter. Biochemical studies have shown, however, that TBP recognizes the TATA-box in both orientations and, therefore, cannot account for...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171774/ https://ncbi.nlm.nih.gov/pubmed/10619841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.1.25 |
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