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Dynamic turnover of paused Pol II complexes at human promoters

Paused RNA polymerase II (Pol II) that piles up near most human promoters is the target of mechanisms that control entry into productive elongation. Whether paused Pol II is a stable or dynamic target remains unresolved. We report that most 5′ paused Pol II throughout the genome is turned over withi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Erickson, Benjamin, Sheridan, Ryan M., Cortazar, Michael, Bentley, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120720/
https://ncbi.nlm.nih.gov/pubmed/30150253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.316810.118
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