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Structural basis of preinitiation complex assembly on human pol II promoters.

Transcription initiation requires the assembly of a preinitiation complex (PIC), which is nucleated through binding of the TATA-box binding protein (TBP) to the promoter. Biochemical studies have shown, however, that TBP recognizes the TATA-box in both orientations and, therefore, cannot account for...

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Hlavní autoři: Tsai, F T, Sigler, P B
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171774/
https://ncbi.nlm.nih.gov/pubmed/10619841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.1.25
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