Direct Recruitment of Polycomb Repressive Complex 1 (PRC1) to Chromatin by Core Binding Transcription Factors

Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian cells remain incompletely understood. In this study, we show that Bmi1, a core component of Polycomb Repressive Complex 1 (PRC1), binds direct...

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Main Authors: Yu, Ming, Mazor, Tali, Huang, Hui, Huang, Hsuan-Ting, Kathrein, Katie L., Woo, Andrew J., Chouinard, Candace R., Labadorf, Adam, Akie, Thomas E., Moran, Tyler B., Xie, Huafeng, Zacharek, Sima, Taniuchi, Ichiro, Roeder, Robert G., Kim, Carla F., Zon, Leonard I., Fraenkel, Ernest, Cantor, Alan B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278717/
https://ncbi.nlm.nih.gov/pubmed/22325351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.032
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