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Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity

Intestinal stem cells (ISCs) are adult multipotent cells essential for the maintenance of intestinal epithelial homeostasis. Wnt signaling activity ensures that the pool of ISCs at the basis of the intestinal crypts is preserved. Dysregulation of the Wnt pathway is often observed in cancer and suppo...

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Bibliografske podrobnosti
izdano v:Stem Cell Investig
Main Authors: Léveillé, Nicolas, Vermeulen, Louis
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958053/
https://ncbi.nlm.nih.gov/pubmed/27488310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.06.03
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