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Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity
Intestinal stem cells (ISCs) are adult multipotent cells essential for the maintenance of intestinal epithelial homeostasis. Wnt signaling activity ensures that the pool of ISCs at the basis of the intestinal crypts is preserved. Dysregulation of the Wnt pathway is often observed in cancer and suppo...
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| Publicado no: | Stem Cell Investig |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958053/ https://ncbi.nlm.nih.gov/pubmed/27488310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.06.03 |
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