Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity

Polycomb group proteins are transcriptional repressors that play a central role in the establishment and maintenance of gene expression patterns during development. Using mice with an N-ethyl-N-nitrosourea (ENU)-induced mutation in Suppressor of Zeste 12 (Suz12), a core component of Polycomb Repress...

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Autores principales: Majewski, Ian J, Blewitt, Marnie E, de Graaf, Carolyn A, McManus, Edward J, Bahlo, Melanie, Hilton, Adrienne A, Hyland, Craig D, Smyth, Gordon K, Corbin, Jason E, Metcalf, Donald, Alexander, Warren S, Hilton, Douglas J
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292752/
https://ncbi.nlm.nih.gov/pubmed/18416604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060093
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