Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration

Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions. Neuronal specification is driven by transcriptional programs that are established during early neuronal development and remain in place in the...

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Udgivet i:Nat Neurosci
Main Authors: von Schimmelmann, Melanie, Feinberg, Philip A., Sullivan, Josefa M., Ku, Stacy M., Badimon, Ana, Duff, Mary Kaye, Wang, Zichen, Lachmann, Alexander, Dewell, Scott, Ma'ayan, Avi, Han, Ming-Hu, Tarakhovsky, Alexander, Schaefer, Anne
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088783/
https://ncbi.nlm.nih.gov/pubmed/27526204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4360
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