Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

Polycomb repressive complex 2 (PRC2) plays a key role in hematopoietic stem and progenitor cell (HSPC) function. Analyses of mouse mutants harboring deletions of core components have implicated PRC2 in fine-tuning multiple pathways that instruct HSPC behavior, yet how PRC2 is targeted to specific ge...

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Udgivet i:Blood
Main Authors: Kinkel, Sarah A., Galeev, Roman, Flensburg, Christoffer, Keniry, Andrew, Breslin, Kelsey, Gilan, Omer, Lee, Stanley, Liu, Joy, Chen, Kelan, Gearing, Linden J., Moore, Darcy L., Alexander, Warren S., Dawson, Mark, Majewski, Ian J., Oshlack, Alicia, Larsson, Jonas, Blewitt, Marnie E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424268/
https://ncbi.nlm.nih.gov/pubmed/25645357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-603969
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