Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

Polycomb repressive complex 2 (PRC2) plays a key role in hematopoietic stem and progenitor cell (HSPC) function. Analyses of mouse mutants harboring deletions of core components have implicated PRC2 in fine-tuning multiple pathways that instruct HSPC behavior, yet how PRC2 is targeted to specific ge...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kinkel, Sarah A., Galeev, Roman, Flensburg, Christoffer, Keniry, Andrew, Breslin, Kelsey, Gilan, Omer, Lee, Stanley, Liu, Joy, Chen, Kelan, Gearing, Linden J., Moore, Darcy L., Alexander, Warren S., Dawson, Mark, Majewski, Ian J., Oshlack, Alicia, Larsson, Jonas, Blewitt, Marnie E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424268/
https://ncbi.nlm.nih.gov/pubmed/25645357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-603969
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