Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice

Leukemia is a complex heterogeneous disease often driven by the expression of oncogenic fusion proteins with different molecular and biochemical properties. Whereas several fusion proteins induce leukemogenesis by activating Hox gene expression (Hox-activating fusions), others impinge on different p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Rossi, Alessandra, Ferrari, Karin J., Piunti, Andrea, Jammula, SriGanesh, Chiacchiera, Fulvio, Mazzarella, Luca, Scelfo, Andrea, Pelicci, Pier Giuseppe, Pasini, Diego
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055382/
https://ncbi.nlm.nih.gov/pubmed/27730210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600972
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