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Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity

Transcription by RNA polymerase II (Pol II) is a complex process that requires general transcription factors and Pol II to assemble on DNA into preinitiation complexes that can begin RNA synthesis upon binding of NTPs (nucleoside triphosphate). The pathways by which preinitiation complexes form, and...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Horn, Abigail E., Kugel, Jennifer F., Goodrich, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009721/
https://ncbi.nlm.nih.gov/pubmed/27112574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw321
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