AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

The positive transcription elongation factor b (P-TEFb) stimulates RNA polymerase elongation by inducing the transition of promoter proximally paused polymerase II into a productively elongating state. P-TEFb itself is regulated by reversible association with various transcription factors/cofactors...

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Hlavní autoři: Lu, Huasong, Li, Zichong, Xue, Yuhua, Schulze-Gahmen, Ursula, Johnson, Jeffrey R., Krogan, Nevan J., Alber, Tom, Zhou, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890890/
https://ncbi.nlm.nih.gov/pubmed/24367103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318503111
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