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Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb
The 7SK small nuclear RNA (snRNA) regulates RNA polymerase II transcription elongation by controlling the protein kinase activity of the positive transcription elongation factor b (P-TEFb). In cooperation with HEXIM1, the 7SK snRNA sequesters P-TEFb into the kinase-inactive 7SK/HEXIM1/P-TEFb small n...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1949012/ https://ncbi.nlm.nih.gov/pubmed/17611602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601783 |
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