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The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression

The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nuclear activity of positive transcription elongation factor b (P‐TEFb). Here, we demonstrate that the huma...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Egloff, Sylvain, Vitali, Patrice, Tellier, Michael, Raffel, Raoul, Murphy, Shona, Kiss, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376971/
https://ncbi.nlm.nih.gov/pubmed/28254838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695740
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