A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP

The 7SK snRNP represents a major reservoir of activity where P-TEFb, a general transcription factor key for RNA polymerase II elongation, can be withdrawn to promote gene expression, cell growth and development. Within this complex, 7SK snRNA is a central scaffold that coordinates key protein–protei...

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Bibliografiske detaljer
Main Authors: Xue, Yuhua, Yang, Zhiyuan, Chen, Ruichuan, Zhou, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811026/
https://ncbi.nlm.nih.gov/pubmed/19906723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp977
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