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Reconstitution of a functional 7SK snRNP

The 7SK small nuclear ribonucleoprotein (snRNP) plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb. We optimized conditions for analyzing 7SK RNA by SHAPE and demonstrated a hysteretic effect of magnesium on 7SK folding dynamics including a 7...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Brogie, John E., Price, David H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499737/
https://ncbi.nlm.nih.gov/pubmed/28431135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx262
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