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7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development
Eukaryotic gene expression is commonly controlled at the level of RNA polymerase II (RNAPII) pausing subsequent to transcription initiation. Transcription elongation is stimulated by the positive transcription elongation factor b (P-TEFb) kinase, which is suppressed within the 7SK small nuclear ribo...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683122/ https://ncbi.nlm.nih.gov/pubmed/19416841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903188106 |
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