7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development

Eukaryotic gene expression is commonly controlled at the level of RNA polymerase II (RNAPII) pausing subsequent to transcription initiation. Transcription elongation is stimulated by the positive transcription elongation factor b (P-TEFb) kinase, which is suppressed within the 7SK small nuclear ribo...

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Bibliografske podrobnosti
Main Authors: Barboric, Matjaz, Lenasi, Tina, Chen, Hui, Johansen, Eric B., Guo, Su, Peterlin, B. Matija
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683122/
https://ncbi.nlm.nih.gov/pubmed/19416841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903188106
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