A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency

Por Li, Zichong, Lu, Huasong, Zhou, Qiang
Publicado no Mol Cell Biol (2016)

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

Por Li, Zichong, Guo, Jia, Wu, Yuntao, Zhou, Qiang
Publicado em 2013

Viral-host interactions that control HIV-1 transcriptional elongation

Por Lu, Huasong, Li, Zichong, Xue, Yuhua, Zhou, Qiang
Publicado no Chem Rev (2013)

The ubiquitin ligase Siah1 controls ELL2 stability and formation of Super Elongation Complexes (SECs) to modulate gene transcription

Por Liu, Min, Hsu, Joanne, Chan, Caleb, Li, Zichong, Zhou, Qiang
Publicado em 2012

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription

Por Lu, Huasong, Li, Zichong, Zhang, Wei, Schulze-Gahmen, Ursula, Xue, Yuhua, Zhou, Qiang
Publicado no Nucleic Acids Res (2015)

Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription

Por Qi, Shiqian, Li, Zichong, Schulze-Gahmen, Ursula, Stjepanovic, Goran, Zhou, Qiang, Hurley, James H.
Publicado no Nat Commun (2017)

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

Por Lu, Huasong, Li, Zichong, Xue, Yuhua, Schulze-Gahmen, Ursula, Johnson, Jeffrey R., Krogan, Nevan J., Alber, Tom, Zhou, Qiang
Publicado em 2014